High prevalence of p53 gene alterations and protein overexpression in human esophageal cancer: correlation with dietary risk factors in India.

Gaur, D; Arora, S; Mathur, M; Nath, N; Chattopadhaya, T K; Ralhan, R

Gaur, D; Arora, S; Mathur, M; Nath, N; Chattopadhaya, T K; Ralhan, R.

Affiliation

Gaur D; Departments of Biochemistry, All India Institute of Medical Sciences, New Delhi 110029, India.

Clin Cancer Res ; 3(11): 2129-36, 1997 Nov.

Article in En | MEDLINE | ID: mdl-9815606

Subject(s)

Carcinoma, Squamous Cell/epidemiology; Carcinoma, Squamous Cell/genetics; Diet; Esophageal Neoplasms/epidemiology; Esophageal Neoplasms/genetics; Genes, p53; Mutation; Tumor Suppressor Protein p53/genetics; Adult; Aged; Carcinogens; Carcinoma, Squamous Cell/chemistry; Carcinoma, Squamous Cell/pathology; Esophageal Neoplasms/chemistry; Esophageal Neoplasms/pathology; Esophagus/metabolism; Esophagus/pathology; Exons; Feeding Behavior; Female; Humans; Immunoblotting; Immunohistochemistry; India/epidemiology; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Risk Factors; Tumor Suppressor Protein p53/analysis

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Database: MEDLINE Main subject: Esophageal Neoplasms / Carcinoma, Squamous Cell / Genes, p53 / Tumor Suppressor Protein p53 / Diet / Mutation Type of study: Etiology_studies / Prevalence_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Year: 1997 Type: Article

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