Synaptophysin and neurofilament expression in neurons infected with dengue virus
Arch. med. res
; 25(2): 215-7, 1994. ilus
Article
en En
| LILACS
| ID: lil-198810
Biblioteca responsable:
MX1.1
ABSTRACT
The expression of two genes encoding the neuronal specific proteins synaptophysin and high molecular weigh neurofilaments was investigated in primary cell cultures of embryonic mouse brain infected with dengue virus type 2, using immunocytochemistry and Western blot analysis with monoclonal antibodies. The viral infection leads to a 20-fold induction in the expression of the mentioned synaptogenesis-related proteins. These results suggest a correlation between virus infection and neuropathology of immature neurons in vivo
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Banco de datos:
LILACS
Asunto principal:
Sinapsis
/
Filamentos Intermedios
/
Western Blotting
/
Virus del Dengue
/
Flavivirus
/
Neuronas
Límite:
Animals
Idioma:
En
Año:
1994
Tipo del documento:
Article