Detection of cerebroside sulfotransferase mRNA in human gastric mucosa and adenocarcinoma.
Cancer Lett
; 138(1-2): 45-51, 1999 Apr 26.
Article
en En
| MEDLINE
| ID: mdl-10378772
ABSTRACT
Sulfatide is a major acidic glycolipid in human gastric mucosa, and its sulfation is catalyzed by cerebroside sulfotransferase (CST). To investigate the expression of the CST gene in human gastric cancer, a reverse transcription PCR method was developed with the use of endoscopic bioptic specimens. By this method, we examined the CST mRNA expression in 11 cases of gastric cancer, and in all the cases we detected various levels of the expression both in cancer tissues and in uninvolved adjacent tissues. The present assay method was suggested to be useful in the detection of CST mRNA from a limited amount of bioptic samples.
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Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Gástricas
/
ARN Mensajero
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Adenocarcinoma
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Sulfotransferasas
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Mucosa Gástrica
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Año:
1999
Tipo del documento:
Article