Pleomorphic lipoma of the orbit: a case series and review of literature.
Ophthalmology
; 110(1): 101-5, 2003 Jan.
Article
en En
| MEDLINE
| ID: mdl-12511353
ABSTRACT
OBJECTIVE:
Pleomorphic lipomas are rare benign tumors that can resemble a variety of malignant soft tissue tumors on histologic examination. Six cases of patients with orbital pleomorphic lipoma, one of which was proven to be bilateral, are presented.DESIGN:
Retrospective, noncomparative, interventional case series with clinicopathologic correlation.METHODS:
Clinical and histologic review of 6 patients with pleomorphic lipomas of the orbit and histologic review of fat from 22 exenteration specimens and 20 other orbital procedures. MAIN OUTCOMEMEASURES:
Evidence of histologic abnormalities in histologic specimens.RESULTS:
Pleomorphic spindle cells and multinucleated cells with nuclei arranged in a floret-like pattern were present in 7 specimens from 6 patients presenting with a clinical diagnosis of orbital fat prolapse, but there were no similar cell types present in the adipose tissue of 22 exenteration or 20 other orbital specimens.CONCLUSION:
Pleomorphic lipoma may arise in the orbit, presenting as what was hitherto considered to be age-related epibulbar prolapse of orbital fat.
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Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Orbitales
/
Lipoma
Tipo de estudio:
Observational_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Año:
2003
Tipo del documento:
Article