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NACP-REP1 polymorphism is not involved in Parkinson's disease: a case-control study in a population sample from southern Italy.
Spadafora, P; Annesi, G; Pasqua, A A; Serra, P; Cirò Candiano, I C; Carrideo, S; Tarantino, P; Civitelli, D; De Marco, E V; Nicoletti, G; Annesi, F; Quattrone, A.
Afiliación
  • Spadafora P; Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy.
Neurosci Lett ; 351(2): 75-8, 2003 Nov 13.
Article en En | MEDLINE | ID: mdl-14583385
ABSTRACT
Contradictory evidence has been reported on the role of the polymorphic mixed dinucleotide repeat (NACP-REP1) of the alpha-synuclein gene as a risk factor for sporadic Parkinson's disease (PD). In the present study we genotyped the NACP-REP1 polymorphism in 189 PD patients from southern Italy and 182 healthy control subjects. We failed to demonstrate an association of any NACP-REP1 allele with PD.
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Banco de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Polimorfismo Genético / Repeticiones de Dinucleótido / Proteínas del Tejido Nervioso Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Año: 2003 Tipo del documento: Article
Buscar en Google
Imprimir
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PubMed Links

Banco de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Polimorfismo Genético / Repeticiones de Dinucleótido / Proteínas del Tejido Nervioso Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Año: 2003 Tipo del documento: Article