Acute felbamate overdose with crystalluria.
Clin Toxicol (Phila)
; 43(3): 189-92, 2005.
Article
en En
| MEDLINE
| ID: mdl-15902793
ABSTRACT
A 3-year-old child developed vomiting, ataxia, and crystalluria after ingestion of approximately 232 mg/kg of felbamate elixir. High-powered polarization microscopy of the urine revealed sharp, needle-like crystals. The analysis of the urine crystals showed unchanged felbamate (80.9%), monocarbamate felbamate (18.8%), and trace amounts of mercapturic acid conjugates of the metabolite 2-phenylpropenal (0.1%). The serum felbamate level 15 h after ingestion was 138 mg/L. Crystalluria and hematuria resolved with intravenous fluid therapy, and the child recovered within 24 h.
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Banco de datos:
MEDLINE
Asunto principal:
Intoxicación
/
Glicoles de Propileno
/
Cálculos Urinarios
/
Anticonvulsivantes
Límite:
Child, preschool
/
Female
/
Humans
Idioma:
En
Año:
2005
Tipo del documento:
Article