Non-invasive coronary artery evaluation with multidetector computed tomography.
Rev Port Cardiol
; 24(5): 667-79, 2005 May.
Article
en En, Pt
| MEDLINE
| ID: mdl-16041964
ABSTRACT
OBJECTIVES:
To evaluate the diagnostic accuracy of 16-slice multidetector spiral computed tomography in the non-invasive detection of coronary artery disease compared to invasive coronary angiography.DESIGN:
Prospective study. PATIENTS We studied 35 patients, 21 men and 14 women, mean age 63.6+/-13.8 years, who underwent elective invasive coronary angiography one week prior to undergoing 16-slice multidetector computed tomography.METHODS:
We used a Toshiba Aquilion 16-slice system. Helical acquisition was performed with breath holding after injection of 140 ml of a contrast agent into a peripheral vein. Cross-sectional images were reconstructed with a slice thickness of 0.5 mm or 1 mm. We set 15 anatomical segments for the coronary tree and the evaluation was performed independently for both techniques. Coronary artery lesions with over 50% reduction in diameter were considered significant. Findings from both techniques were evaluated using ROC curve analysis.RESULTS:
It was possible to evaluate 87.7% of the coronary tree segments; heavy calcification, enability to perform breath holding, motion artefacts and stents made evaluation of the other segments impossible. Overall sensitivity and specificity were 85.9% and 98.2% respectively with a 95 % confidence interval; positive predictive value was 87% and negative predictive value 97% For the different anatomical segments, sensitivity and specificity were proximal 88.9% and 97.8%; medial 90.9% and 95.8%; distal 86.7% and 99.1% respectively.CONCLUSIONS:
Multidetector computed tomography is a promising non-invasive technique for detecting or ruling out significant coronary lesions.
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Banco de datos:
MEDLINE
Asunto principal:
Angiografía Coronaria
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Enfermedad Coronaria
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Tomografía Computarizada Espiral
Tipo de estudio:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
/
Pt
Año:
2005
Tipo del documento:
Article