ERM proteins in epithelial cell organization and functions.
Biochim Biophys Acta
; 1773(5): 653-60, 2007 May.
Article
en En
| MEDLINE
| ID: mdl-16904765
ABSTRACT
ERM (Ezrin, Radixin, Moesin) proteins are membrane-cytoskeleton linkers that regulate the structure and the function of specific domains of the plasma membrane. ERM proteins are expressed in all metazoan analyzed so far. Genetic analysis of ERM protein functions has recently been performed simultaneously in three different organisms, mouse, Drosophila melanogaster and C. elegans. These studies have revealed a remarkable conservation of the protein functions through evolution. Moreover they have shed light on the crucial role these proteins play in various physiological processes that occur in epithelial cells.
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Banco de datos:
MEDLINE
Asunto principal:
Citoesqueleto
/
Membrana Celular
/
Proteínas del Citoesqueleto
/
Células Epiteliales
/
Proteínas de la Membrana
/
Proteínas de Microfilamentos
Límite:
Animals
Idioma:
En
Año:
2007
Tipo del documento:
Article