Zinc transporter 7 is located in the cis-Golgi apparatus of mouse choroid epithelial cells.
Neuroreport
; 17(17): 1807-11, 2006 Nov 27.
Article
en En
| MEDLINE
| ID: mdl-17164669
ABSTRACT
The cellular localization of zinc transporter 7 protein in the mouse choroid plexus was examined in this study. Zinc transporter 7 immunoreactive cells were detected in the third, lateral, and fourth ventricles of CD-1 mouse brain. Distinct zinc transporter 7 immunoreactivity was concentrated in the perinuclear regions of the positive cells. The results from zinc autometallography showed that zinc-positive grains were also predominantly located in the perinuclear areas. Ultrastructural localization showed that zinc transporter 7 immunostaining was predominantly present in the membrane and cisternae of the cis-Golgi networks and some vesicle compartments. The results support the notion that zinc transporter 7 may participate in the transport of the cytoplasmic zinc into the Golgi apparatus, and may be involved in local packaging of zinc-binding proteins in the mouse choroid plexus.
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Banco de datos:
MEDLINE
Asunto principal:
Proteínas Portadoras
/
Plexo Coroideo
/
Células Epiteliales
/
Aparato de Golgi
Límite:
Animals
Idioma:
En
Año:
2006
Tipo del documento:
Article