Novel class of hybrid natural products derived from lupeol as antimalarial agents.
Nat Prod Res
; 22(4): 305-19, 2008 Mar 10.
Article
en En
| MEDLINE
| ID: mdl-18322846
ABSTRACT
Thirty-four novel hybrid lupeol derivatives (4-18) were prepared and evaluated for antimalarial activity in vitro against Plasmodium falciparum. Three compounds (13d, 16a and 17a) have shown antimalarial activity at lower dose (10 microg mL(-1)) than lupeol.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Triterpenos
/
Antimaláricos
Idioma:
En
Año:
2008
Tipo del documento:
Article