Relations between open-field, elevated plus-maze, and emergence tests as displayed by C57/BL6J and BALB/c mice.
J Neurosci Methods
; 171(1): 48-52, 2008 Jun 15.
Article
en En
| MEDLINE
| ID: mdl-18358538
ABSTRACT
The relations between open-field, elevated plus-maze, and emergence tests were examined in two strains of mice. In the open-field, C57BL/6J mice had more ambulatory movements and rears but not stereotyped movements relative to BALB/c. In addition, C57BL/6J mice entered more often than BALB/c into enclosed and open arms of the elevated plus-maze. When placed inside a large enclosure, C57BL/6J mice emerged more quickly than BALB/c from a small toy object. In the entire series of mice, ambulation and rears in the open-field were linearly correlated with open and enclosed arm visits in the elevated plus-maze. Ambulatory movements and rears were also correlated with emergence latencies. In contrast, stereotyped movements were correlated with emergence latencies, but not with any elevated plus-maze value. These results specify the extent and limits of association between the three tests.
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1
Banco de datos:
MEDLINE
Asunto principal:
Reacción de Prevención
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Aprendizaje por Laberinto
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Conducta Exploratoria
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Ratones Endogámicos BALB C
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Ratones Endogámicos C57BL
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Animals
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En
Año:
2008
Tipo del documento:
Article