Epilepsy surgery in tuberous sclerosis complex: early predictive elements and outcome.
Childs Nerv Syst
; 24(12): 1437-45, 2008 Dec.
Article
en En
| MEDLINE
| ID: mdl-18704447
ABSTRACT
AIM:
The aim of the study was to evaluate the surgical treatment of epilepsy and detection of possible early surgery predictive elements in patients with tuberous sclerosis complex (TSC). MATERIALS ANDMETHODS:
Forty-two TSC patients with epilepsy were selected and divided into two main groups definite and fruste forms. Definite forms were divided into different groups patients with pharmacologically controlled epilepsy, patients with pharmacoresistant epilepsy excluded from surgery after an extensive presurgical assessment, and patients with a pharmacoresistant epilepsy who underwent surgery. We compared the definite TSC groups to identify elements that predict surgical candidacy. Second, we compared all operated patients to assess surgical outcome.CONCLUSION:
We found several factors that could predict a surgical intervention even if identification of patients with refractory epilepsy who can benefit from surgery is an evolving process. Also, several positive factors for good surgical outcome were identified. Patients with the fruste form had excellent surgical outcome.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Esclerosis Tuberosa
/
Epilepsia
Tipo de estudio:
Etiology_studies
/
Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
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Adult
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Child
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Child, preschool
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Female
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Humans
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Male
Idioma:
En
Año:
2008
Tipo del documento:
Article