Reliability of ventilatory parameters during cycle ergometry in multicentre trials in COPD.
Eur Respir J
; 34(4): 866-74, 2009 Oct.
Article
en En
| MEDLINE
| ID: mdl-19282342
ABSTRACT
We studied the distribution profiles and repeatability of key exercise performance parameters in the first large multicentre trials to include these measurements in chronic obstructive pulmonary disease (COPD). After a screening visit, 463 subjects with COPD (mean+/-SD forced expiratory volume in 1 s 43+/-13% predicted) completed two run-in visits before treatment randomisation. At the run-in visits, measurements were conducted at rest, at a standardised time near end-exercise (isotime) and at peak exercise during constant work rate (CWR) cycle tests at 75% of each individual's maximum work capacity. The intraclass correlation coefficient was used to evaluate the test-retest repeatability of measurements of endurance time (ET), inspiratory capacity (IC), ventilation and dyspnoea intensity (Borg scale) during exercise. IC, ventilation and dyspnoea ratings were normally distributed; ET showed rightward skew (median
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Pruebas de Función Respiratoria
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Tolerancia al Ejercicio
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Enfermedad Pulmonar Obstructiva Crónica
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Prueba de Esfuerzo
Tipo de estudio:
Clinical_trials
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Diagnostic_studies
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Prognostic_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2009
Tipo del documento:
Article