Pyridine-based heterocycles. Synthesis of new pyrido [4',3':4,5]thieno[2,3-d]pyrimidines and related heterocycles.
Molecules
; 15(4): 2651-66, 2010 Apr 12.
Article
en En
| MEDLINE
| ID: mdl-20428071
ABSTRACT
The synthesis of the title compounds was achieved using ethyl 2-amino-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (1) as starting material. The reaction of the amino ester 1 with phenylisothiocyanate in boiling ethanol afforded the thiourea derivative 5. The cyclization reactions of 5 under different reaction conditions led to different pyridothienopyrimidine derivatives. Other reactions of the latter derivatives leading to pyrido[4',3'4,5]thieno[2,3-d]triazolo[1,5-a]pyrimidines are also presented.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Piridinas
/
Pirimidinas
/
Compuestos Heterocíclicos
Idioma:
En
Año:
2010
Tipo del documento:
Article