Lipidomics era: accomplishments and challenges.
Mass Spectrom Rev
; 29(6): 877-929, 2010.
Article
en En
| MEDLINE
| ID: mdl-20931646
ABSTRACT
Lipid mediators participate in signal transduction pathways, proliferation, apoptosis, and membrane trafficking in the cell. Lipids are highly complex and diverse owing to the various combinations of polar headgroups, fatty acyl chains, and backbone structures. This structural diversity continues to pose a challenge for lipid analysis. Here we review the current state of the art in lipidomics research and discuss the challenges facing this field. The latest technological developments in mass spectrometry, the role of bioinformatics, and the applications of lipidomics in lipid metabolism and cellular physiology and pathology are also discussed.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Metabolismo de los Lípidos
/
Metabolómica
/
Lípidos
Límite:
Humans
Idioma:
En
Año:
2010
Tipo del documento:
Article