New cytotoxic prostanoids from Taiwanese soft coral Clavularia viridis.
Chem Biodivers
; 7(11): 2702-8, 2010 Nov.
Article
en En
| MEDLINE
| ID: mdl-21072769
ABSTRACT
Chemical investigation of the AcOEt/MeOH extract of Clavularia viridis collected in Taiwan has afforded four new prostanoids, named claviridins A-D (1-4, resp.). The structures of compounds 1-4 were determined on the basis of 1D- and 2D-NMR techniques, including COSY, HMQC, HMBC, and NOESY experiments. Pharmacological studies revealed that compounds 1-4 exhibited potent cytotoxicity against human cancer cells.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Prostaglandinas
/
Antozoos
Límite:
Animals
/
Humans
País/Región como asunto:
Asia
Idioma:
En
Año:
2010
Tipo del documento:
Article