Management of granulomatous mastitis: a series of 14 patients.
Gynecol Endocrinol
; 28(11): 921-4, 2012 Nov.
Article
en En
| MEDLINE
| ID: mdl-22731702
ABSTRACT
OBJECTIVE:
To analyze the history of relapses in idiopathic granulomatous mastitis (IGM) and to define an appropriate therapeutic strategy. The duration and number of relapses are unpredictable, and the roles of surgery and corticosteroids remain controversial. STUDYDESIGN:
A series of 14 patients with IGM and a mean follow-up of 61.5 ± 73 (SD) months were retrospectively studied in the Gynecology Unit (Hotel Dieu Hospital, Paris, France). Main outcome measure was number of relapses per year before and following corticosteroid therapy. Comparison of the two groups was performed with matched t-test.RESULTS:
A total of 125 episodes were analyzed. Before steroid treatment, 60 recurrences occurred, corresponding to a mean of 4.03 ± 4.22 (SD) relapses per year. After the first treatment with prednisone, patients experienced 47 relapses, representing a mean of 1.11 ± 1.27 (SD) relapses per year (p = 0.0371).CONCLUSIONS:
Medical treatment with steroid reduces the duration and number of episodes. It also prevents the need for invasive breast surgery.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Corticoesteroides
/
Mastitis Granulomatosa
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
En
Año:
2012
Tipo del documento:
Article