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Enhancing integrin α1 inserted (I) domain affinity to ligand potentiates integrin α1ß1-mediated down-regulation of collagen synthesis.
Shi, Mingjian; Pedchenko, Vadim; Greer, Briana H; Van Horn, Wade D; Santoro, Samuel A; Sanders, Charles R; Hudson, Billy G; Eichman, Brandt F; Zent, Roy; Pozzi, Ambra.
Afiliación
  • Shi M; Department of Medicine (Nephrology), Vanderbilt University, Nashville, Tennessee 37232.
  • Pedchenko V; Department of Medicine (Nephrology), Vanderbilt University, Nashville, Tennessee 37232; Center for Matrix Biology, Vanderbilt University, Nashville, Tennessee 37232.
  • Greer BH; Center for Structural Biology, Vanderbilt University, Nashville, Tennessee 37232; Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37232.
  • Van Horn WD; Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37232; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee 37232.
  • Santoro SA; Center for Matrix Biology, Vanderbilt University, Nashville, Tennessee 37232; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, Tennessee 37232.
  • Sanders CR; Center for Matrix Biology, Vanderbilt University, Nashville, Tennessee 37232; Center for Structural Biology, Vanderbilt University, Nashville, Tennessee 37232; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee 37232.
  • Hudson BG; Department of Medicine (Nephrology), Vanderbilt University, Nashville, Tennessee 37232; Center for Matrix Biology, Vanderbilt University, Nashville, Tennessee 37232; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee 37232.
  • Eichman BF; Center for Matrix Biology, Vanderbilt University, Nashville, Tennessee 37232; Center for Structural Biology, Vanderbilt University, Nashville, Tennessee 37232; Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37232; Department of Biochemistry, Vanderbilt University, Nas
  • Zent R; Department of Medicine (Nephrology), Vanderbilt University, Nashville, Tennessee 37232; Center for Matrix Biology, Vanderbilt University, Nashville, Tennessee 37232; Department of Medicine, Veterans Affairs Medical Center, Nashville, Tennessee 37212.
  • Pozzi A; Department of Medicine (Nephrology), Vanderbilt University, Nashville, Tennessee 37232; Center for Matrix Biology, Vanderbilt University, Nashville, Tennessee 37232; Department of Medicine, Veterans Affairs Medical Center, Nashville, Tennessee 37212. Electronic address: ambra.pozzi@vanderbilt.edu.
J Biol Chem ; 287(42): 35139-35152, 2012 Oct 12.
Article en En | MEDLINE | ID: mdl-22888006

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Biosíntesis de Proteínas / Modelos Moleculares / Regulación hacia Abajo / Laminina / Sistema de Señalización de MAP Quinasas / Colágeno Tipo IV / Integrina alfa1beta1 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2012 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Biosíntesis de Proteínas / Modelos Moleculares / Regulación hacia Abajo / Laminina / Sistema de Señalización de MAP Quinasas / Colágeno Tipo IV / Integrina alfa1beta1 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2012 Tipo del documento: Article