Applications for nitric oxide in halting proliferation of tumor cells.
Biochem Biophys Res Commun
; 431(4): 647-51, 2013 Feb 22.
Article
en En
| MEDLINE
| ID: mdl-23337501
ABSTRACT
Tumor resistance to cytotoxic therapeutics coupled with dose-limiting toxicity is a serious hurdle in the field of medical oncology. In the face of this obstacle, nitric oxide has emerged as a powerful adjuvant for the hypersensitization of tumors to more traditional chemo- and radio-therapeutics. Furthermore, emerging evidence indicates that nitric oxide donors have the potential to function independently in the clinical management of cancer. Herein, we discuss the role of nitric oxide in cancer and the potential for nitric oxide donors to support conventional therapeutics.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Resistencia a Antineoplásicos
/
Donantes de Óxido Nítrico
/
Proliferación Celular
/
Neoplasias
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Óxido Nítrico
Límite:
Humans
Idioma:
En
Año:
2013
Tipo del documento:
Article