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Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval.
Avery, C L; Sitlani, C M; Arking, D E; Arnett, D K; Bis, J C; Boerwinkle, E; Buckley, B M; Ida Chen, Y-D; de Craen, A J M; Eijgelsheim, M; Enquobahrie, D; Evans, D S; Ford, I; Garcia, M E; Gudnason, V; Harris, T B; Heckbert, S R; Hochner, H; Hofman, A; Hsueh, W-C; Isaacs, A; Jukema, J W; Knekt, P; Kors, J A; Krijthe, B P; Kristiansson, K; Laaksonen, M; Liu, Y; Li, X; Macfarlane, P W; Newton-Cheh, C; Nieminen, M S; Oostra, B A; Peloso, G M; Porthan, K; Rice, K; Rivadeneira, F F; Rotter, J I; Salomaa, V; Sattar, N; Siscovick, D S; Slagboom, P E; Smith, A V; Sotoodehnia, N; Stott, D J; Stricker, B H; Stürmer, T; Trompet, S; Uitterlinden, A G; van Duijn, C.
Afiliación
  • Avery CL; Department of Epidemiology, Bank of America Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Sitlani CM; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.
  • Arking DE; McKusick-Nathans Institute of Genetic Medicine and Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Arnett DK; Department of Epidemiology, The University of Alabama at Birmingham, Birmingham, AL, USA.
  • Bis JC; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.
  • Boerwinkle E; Division of Epidemiology and Center for Human Genetics, The University of Texas Health Science Center, Houston, TX, USA.
  • Buckley BM; Department of Pharmacology and Therapeutics, University College Cork, Cork, UK.
  • Ida Chen YD; Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • de Craen AJ; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.
  • Eijgelsheim M; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Enquobahrie D; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.
  • Evans DS; California Pacific Medical Center Research Institute, San Francisco, CA, USA.
  • Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK.
  • Garcia ME; Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD, USA.
  • Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.
  • Harris TB; Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD, USA.
  • Heckbert SR; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA [2] Department of Epidemiology, University of Washington, Seattle, WA, USA.
  • Hochner H; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.
  • Hofman A; 1] Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands.
  • Hsueh WC; Department of Medicine, University of California, San Francisco, CA, USA.
  • Isaacs A; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Centre for Medical Systems Biology, Leiden, The Netherlands.
  • Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Knekt P; THL-National Institute for Health and Welfare, Helsinki, Finland.
  • Kors JA; 1] Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands [2] Department of Medical Informatics, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Krijthe BP; 1] Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands.
  • Kristiansson K; THL-National Institute for Health and Welfare, Helsinki, Finland.
  • Laaksonen M; THL-National Institute for Health and Welfare, Helsinki, Finland.
  • Liu Y; Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University, Winston-Salem, NC, USA.
  • Li X; Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Macfarlane PW; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
  • Newton-Cheh C; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA [2] Center for Human Genetic Research, Cardiovascular Research Center, Harvard Medical School, Boston, MA, USA [3] Massachusetts General Hospital, Boston, MA, USA.
  • Nieminen MS; Division of Cardiology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland.
  • Oostra BA; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Centre for Medical Systems Biology, Leiden, The Netherlands.
  • Peloso GM; 1] National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.
  • Porthan K; Division of Cardiology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland.
  • Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Rivadeneira FF; 1] Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands [3] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Rotter JI; Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Salomaa V; THL-National Institute for Health and Welfare, Helsinki, Finland.
  • Sattar N; BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, Glasgow, UK.
  • Siscovick DS; 1] Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA [2] Department of Epidemiology, University of Washington, Seattle, WA, USA.
  • Slagboom PE; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Smith AV; Icelandic Heart Association, Kopavogur, Iceland.
  • Sotoodehnia N; Division of Cardiology, University of Washington, Seattle, WA, USA.
  • Stott DJ; Academic Section of Geriatric Medicine, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
  • Stricker BH; 1] Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands [3] Department of Medical Informatics, Erasmus Medical Center, Rotterdam, The Netherlands [4] Department of Internal Medicine, Erasmus Medica
  • Stürmer T; Department of Epidemiology, Bank of America Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Uitterlinden AG; 1] Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands [3] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
  • van Duijn C; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Centre for Medical Systems Biology, Leiden, The Netherlands.
Pharmacogenomics J ; 14(1): 6-13, 2014 Feb.
Article en En | MEDLINE | ID: mdl-23459443
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Farmacogenética / Síndrome de QT Prolongado / Carácter Cuantitativo Heredable / Polimorfismo de Nucleótido Simple / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Interacción Gen-Ambiente Tipo de estudio: Health_economic_evaluation / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Farmacogenética / Síndrome de QT Prolongado / Carácter Cuantitativo Heredable / Polimorfismo de Nucleótido Simple / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Interacción Gen-Ambiente Tipo de estudio: Health_economic_evaluation / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Año: 2014 Tipo del documento: Article