Genotoxicity and oxidative stress in gasoline station attendants.
Mutat Res
; 754(1-2): 63-70, 2013 Jun 14.
Article
en En
| MEDLINE
| ID: mdl-23628435
ABSTRACT
We evaluated genotoxic effects of exposure to low levels of benzene, a class I human carcinogen, among gasoline station attendants (GSA). Oxidative stress and the protective effects of antioxidants on DNA damage were also analyzed. Although exposures were below ACGIH (American Conference of Governmental Industrial Hygienists) limits, the GSA group presented higher DNA damage indices and micronucleus frequencies, increased oxidative protein damage, and decreased antioxidant capacity relative to the control group. Duration of benzene exposure was correlated with DNA and protein damage. The biomarkers evaluated in this work may provide early signals of damage in subjects occupationally exposed to benzene.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Gasolina
/
Exposición Profesional
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Estrés Oxidativo
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Pruebas de Mutagenicidad
Límite:
Humans
Idioma:
En
Año:
2013
Tipo del documento:
Article