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Identification of potent and orally bioavailable nucleotide competing reverse transcriptase inhibitors: in vitro and in vivo optimization of a series of benzofurano[3,2-d]pyrimidin-2-one derived inhibitors.
Sturino, Claudio F; Bousquet, Yves; James, Clint A; DeRoy, Patrick; Duplessis, Martin; Edwards, Paul J; Halmos, Ted; Minville, Joannie; Morency, Louis; Morin, Sébastien; Thavonekham, Bounkham; Tremblay, Martin; Duan, Jianmin; Ribadeneira, Maria; Garneau, Michel; Pelletier, Alex; Tremblay, Sonia; Lamorte, Louie; Bethell, Richard; Cordingley, Michael G; Rajotte, Daniel; Simoneau, Bruno.
Afiliación
  • Sturino CF; Department of Chemistry, Boehringer Ingelheim (Canada) Ltd, Research and Development, 2100 Cunard Street, Laval, Québec, Canada H7S 2G5.
Bioorg Med Chem Lett ; 23(13): 3967-75, 2013 Jul 01.
Article en En | MEDLINE | ID: mdl-23673016
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Pirimidinonas / Benzofuranos / VIH / Inhibidores de la Transcriptasa Inversa / Transcriptasa Inversa del VIH Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Año: 2013 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Pirimidinonas / Benzofuranos / VIH / Inhibidores de la Transcriptasa Inversa / Transcriptasa Inversa del VIH Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Año: 2013 Tipo del documento: Article