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The allosteric mechanism of activation of antithrombin as an inhibitor of factor IXa and factor Xa: heparin-independent full activation through mutations adjacent to helix D.
Dementiev, Alexey; Swanson, Richard; Roth, Ryan; Isetti, Giulia; Izaguirre, Gonzalo; Olson, Steven T; Gettins, Peter G W.
Afiliación
  • Dementiev A; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois 60607.
  • Swanson R; Center for Molecular Biology of Oral Disease, University of Illinois at Chicago, Chicago, Illinois 60607.
  • Roth R; Center for Molecular Biology of Oral Disease, University of Illinois at Chicago, Chicago, Illinois 60607.
  • Isetti G; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois 60607.
  • Izaguirre G; Center for Molecular Biology of Oral Disease, University of Illinois at Chicago, Chicago, Illinois 60607.
  • Olson ST; Center for Molecular Biology of Oral Disease, University of Illinois at Chicago, Chicago, Illinois 60607.
  • Gettins PGW; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois 60607. Electronic address: pgettins@uic.edu.
J Biol Chem ; 288(47): 33611-33619, 2013 Nov 22.
Article en En | MEDLINE | ID: mdl-24068708
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factor IXa / Factor Xa / Antitrombina III / Mutación Límite: Humans Idioma: En Año: 2013 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factor IXa / Factor Xa / Antitrombina III / Mutación Límite: Humans Idioma: En Año: 2013 Tipo del documento: Article