Serum amyloid A and Omentin levels in acute appendicitis: a preliminary study for a novel diagnostic approach.
Clin Ter
; 165(1): e35-8, 2014.
Article
en En
| MEDLINE
| ID: mdl-24589958
ABSTRACT
BACKGROUND:
The diagnosis of acute appendicitis is based on medical history and physical examination. Serum (S) amiloid A (AA) levels are elevated in many inflammatory conditions. Omentin is a recently discovered adipokine showing decreased levels associated with inflammatory conditions. We aimed to measure SAA and omentin levels in patients with acute appendicitis. MATERIALS ANDMETHODS:
36 patients with a diagnosis of acute appendicitis and 30 healthy subjects were enrolled to this research study. A statistical analysis was performed using IBM SPSS Statistics Version 16.0 (SPSS Inc.®, Chicago, IL, United States).RESULTS:
Patients in study group were significantly older than healthy control subjects (p=0.013). Body mass index of the patients with acute appendicitis (23.2 ± 1.3) was greater than that of the control group (22.7 ± 1), but the difference did not reach the statistically significance (p=0.076). ). Mean level of SAA was significantly raised in study group compared to healthy control subjects (p< 0.001). Mean omentin level was significantly lower in study group compared to healthy subjects (p=0.013).CONCLUSIONS:
In conclusion, although diagnosis of acute appendicitis is mostly based on clinical findings, omentin and especially SAA measurement in serum may help surgeons to avoid negative laparatomy.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Apendicitis
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Proteína Amiloide A Sérica
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Citocinas
/
Lectinas
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
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Female
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Humans
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Male
Idioma:
En
Año:
2014
Tipo del documento:
Article