Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass.
Neurosci Bull
; 30(2): 243-52, 2014 Apr.
Article
en En
| MEDLINE
| ID: mdl-24733654
ABSTRACT
Considerable debate and controversy surround the cause(s) of Alzheimer's disease (AD). To date, several theories have gained notoriety, however none is universally accepted. In this review, we provide evidence for the oxidative stress-induced AD cascade that posits aged mitochondria as the critical origin of neurodegeneration in AD.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Estrés Oxidativo
/
Enfermedad de Alzheimer
/
Neuronas
Límite:
Humans
Idioma:
En
Año:
2014
Tipo del documento:
Article