Rapid production of platelet-activating factor is induced by protein kinase C&#945;-mediated phosphorylation of lysophosphatidylcholine acyltransferase 2 protein.

Morimoto, Ryo; Shindou, Hideo; Tarui, Megumi; Shimizu, Takao

Rapid production of platelet-activating factor is induced by protein kinase Cα-mediated phosphorylation of lysophosphatidylcholine acyltransferase 2 protein.

Morimoto, Ryo; Shindou, Hideo; Tarui, Megumi; Shimizu, Takao.

Afiliación

Morimoto R; From the Department of Lipid Signaling, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan, the Department of Biochemistry and Molecular Biology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, J
Shindou H; From the Department of Lipid Signaling, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan, the Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama 332-0
Tarui M; From the Department of Lipid Signaling, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
Shimizu T; From the Department of Lipid Signaling, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan, the Department of Biochemistry and Molecular Biology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, J

J Biol Chem ; 289(22): 15566-76, 2014 May 30.

Article en En | MEDLINE | ID: mdl-24742674

Asunto(s)

1-Acilglicerofosfocolina O-Aciltransferasa/metabolismo; Inflamación/metabolismo; Macrófagos Peritoneales/metabolismo; Factor de Activación Plaquetaria/metabolismo; Proteína Quinasa C-alfa/metabolismo; 1-Acilglicerofosfocolina O-Aciltransferasa/genética; Animales; Células CHO; Cricetulus; Técnicas de Silenciamiento del Gen; Lipopolisacáridos/farmacología; Ratones; Ratones Endogámicos C57BL; Fosforilación/inmunología; Proteína Quinasa C-alfa/genética; Serina/metabolismo; Transducción de Señal/inmunología

Palabras clave

Enzyme Catalysis; Inflammation; Lysophospholipid Acyltransferase; Macrophages; Membrane Lipids; Phosphorylation; Platelet-activating Factor; Protein Kinase C (PKC)

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factor de Activación Plaquetaria / Macrófagos Peritoneales / Proteína Quinasa C-alfa / Inflamación / 1-Acilglicerofosfocolina O-Aciltransferasa Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2014 Tipo del documento: Article

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