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Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells.
Roos, Martina; Rebhan, Mario A E; Lucic, Matije; Pavlicek, David; Pradere, Ugo; Towbin, Harry; Civenni, Gianluca; Catapano, Carlo V; Hall, Jonathan.
Afiliación
  • Roos M; Department of Chemistry and Applied Biosciences, ETH Zurich, CH-8093 Zurich, Switzerland.
  • Rebhan MA; Department of Chemistry and Applied Biosciences, ETH Zurich, CH-8093 Zurich, Switzerland.
  • Lucic M; Department of Chemistry and Applied Biosciences, ETH Zurich, CH-8093 Zurich, Switzerland.
  • Pavlicek D; Department of Chemistry and Applied Biosciences, ETH Zurich, CH-8093 Zurich, Switzerland.
  • Pradere U; Department of Chemistry and Applied Biosciences, ETH Zurich, CH-8093 Zurich, Switzerland.
  • Towbin H; Department of Chemistry and Applied Biosciences, ETH Zurich, CH-8093 Zurich, Switzerland.
  • Civenni G; Tumor Biology and Experimental Therapeutics Program, Institute of Oncology Research, Via Vela 6, Bellinzona CH-6500, Switzerland.
  • Catapano CV; Tumor Biology and Experimental Therapeutics Program, Institute of Oncology Research, Via Vela 6, Bellinzona CH-6500, Switzerland.
  • Hall J; Department of Chemistry and Applied Biosciences, ETH Zurich, CH-8093 Zurich, Switzerland jonathan.hall@pharma.ethz.ch.
Nucleic Acids Res ; 43(2): e9, 2015 Jan.
Article en En | MEDLINE | ID: mdl-25378324
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oligorribonucleótidos / Procesamiento Postranscripcional del ARN / Proteínas de Unión al ARN / MicroARNs / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oligorribonucleótidos / Procesamiento Postranscripcional del ARN / Proteínas de Unión al ARN / MicroARNs / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article