Fronto-parietal connectivity changes following noxious stimulation during anesthesia.
J Med Life
; 7(3): 387-90, 2014 Sep 15.
Article
en En
| MEDLINE
| ID: mdl-25408761
ABSTRACT
RATIONALE The aim of our study was to assess the changes in the fronto-parietal connectivity estimated by the cross approximate entropy (XAppEn) during noxious stimulation while under chloral hydrate anaesthesia, in rats. METHOD:
A group of 11 Wistar rats chronically implanted with Ni-Cr electrodes, which were placed on the dura mater of the right hemisphere (over the olfactory cortex, the frontal and the parietal lobes), were used in the present study. Noxious stimuli of a mechanical and thermal nature were applied on the left hindpaw during chloral hydrate anesthesia. The anesthetic depth was estimated through median frequency computation, which in that instance was of 2-3 Hz. Fronto-parietal functional cortical connectivity was assessed by using XAppEn.RESULTS:
After data processing and analysis we observed an increase of fronto-parietal functional connectivity during mechanical and thermal noxious stimulation. In addition, MEF increased both in frontal and parietal areas during the mechanical and thermal stimulation compared to baseline.CONCLUSION:
Mechanical and thermal stimulation induces an increase in the fronto-parietal connectivity during chloral hydrate anesthesia in rats.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Anestesia
/
Red Nerviosa
Límite:
Animals
Idioma:
En
Año:
2014
Tipo del documento:
Article