Heparin-coated dialyzer membranes: is non-inferiority good enough?
Kidney Int
; 86(6): 1084-6, 2014 Dec.
Article
en En
| MEDLINE
| ID: mdl-25427085
ABSTRACT
Evidence on the optimal anticoagulation regimen for hemodialysis in patients at high bleeding risk is scarce. The HepZero study is the first large multinational study comparing two different anticoagulation strategies to avoid systemic heparinization. The use of a heparin-coated dialysis membrane proved to be non-inferior to saline infusion. Superiority of either treatment, however, could not be demonstrated. These findings challenge current guidelines but equally raise questions on the choice of either strategy as compared with regional citrate anticoagulation.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Heparina
/
Diálisis Renal
/
Membranas Artificiales
/
Anticoagulantes
Tipo de estudio:
Guideline
Límite:
Female
/
Humans
/
Male
Idioma:
En
Año:
2014
Tipo del documento:
Article