Polyubiquitin Drives the Molecular Interactions of the NF-&#954;B Essential Modulator (NEMO) by Allosteric Regulation.

Catici, Dragana A M; Horne, James E; Cooper, Grace E; Pudney, Christopher R

Polyubiquitin Drives the Molecular Interactions of the NF-κB Essential Modulator (NEMO) by Allosteric Regulation.

Catici, Dragana A M; Horne, James E; Cooper, Grace E; Pudney, Christopher R.

Afiliación

Catici DA; From the Department of Biology and Biochemistry, Faculty of Science, University of Bath, Bath BA2 7AY, United Kingdom.
Horne JE; From the Department of Biology and Biochemistry, Faculty of Science, University of Bath, Bath BA2 7AY, United Kingdom.
Cooper GE; From the Department of Biology and Biochemistry, Faculty of Science, University of Bath, Bath BA2 7AY, United Kingdom.
Pudney CR; From the Department of Biology and Biochemistry, Faculty of Science, University of Bath, Bath BA2 7AY, United Kingdom c.r.pudney@bath.ac.uk.

J Biol Chem ; 290(22): 14130-9, 2015 May 29.

Article en En | MEDLINE | ID: mdl-25866210

Asunto(s)

Regulación Alostérica; Quinasa I-kappa B/metabolismo; FN-kappa B/metabolismo; Poliubiquitina/metabolismo; Sitio Alostérico; Dicroismo Circular; Humanos; Ligandos; Liposomas/química; Presión; Estructura Secundaria de Proteína; Transducción de Señal; Espectrometría de Fluorescencia; Temperatura; Ubiquitina/metabolismo

Palabras clave

NEMO; adaptor protein; allosteric regulation; biophysics; conformational change; high pressure; polyubiquitin chain

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: FN-kappa B / Poliubiquitina / Regulación Alostérica / Quinasa I-kappa B Tipo de estudio: Prognostic_studies / Qualitative_research Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article

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