A rationally designed peptidomimetic biosensor for sialic acid on cell surfaces.
Chem Commun (Camb)
; 51(38): 8112-5, 2015 May 11.
Article
en En
| MEDLINE
| ID: mdl-25868668
ABSTRACT
We have developed peptidomimetic sialic acid (Sia) biosensors using boronic acid and arginine groups on the peptide backbone. The designed peptides were conjugated to fluorescent streptavidin via biotin enabling the optical labeling of cells. This approach provides unique opportunities to detect Sia composition on the cell surfaces and filopodia.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Oligopéptidos
/
Técnicas Biosensibles
/
Ácido N-Acetilneuramínico
/
Peptidomiméticos
Límite:
Animals
/
Humans
Idioma:
En
Año:
2015
Tipo del documento:
Article