Chinese patients with major depression: Do concomitant pain symptoms affect quality of life independently of severity of depression?
Int J Psychiatry Clin Pract
; 19(3): 174-81, 2015.
Article
en En
| MEDLINE
| ID: mdl-25946899
ABSTRACT
OBJECTIVE:
This study investigated whether painful physical symptoms (PPSs) influenced quality of life (QoL) when adjusting for severity of depression.METHODS:
Severity of depression, QoL and PPSs were assessed at baseline and 3 months among the Chinese cohort (n = 300) of a 3-month observational study of major depressive disorder (MDD) in East Asia. The presence of PPS was defined as 'a mean score of ≥2 on the Somatic Symptom Inventory pain-related items'. Regression analyses determined predictors of QoL at 3 months, adjusting for age, sex, depressive symptoms, overall severity and QoL at baseline.RESULTS:
PPSs were present (PPS+) at baseline in 35.3% of patients. Over 3 months, in the whole sample, EuroQoL visual analogue scale (EQ-VAS) score improved from 45.5 (standard deviation [SD] 20.9) to 81 (SD 16.7), and EuroQoL 5-Dimension Questionnaire (EQ-5D) score improved from 0.52 (SD 0.31) to 0.89 (0.16). At 3 months, mean EQ-VAS was 75.9 (SD 17.7) for PPS+ versus 83.7 (SD 15.6) for PPS-, and mean EQ-5D was 0.83 (SD 0.17) versus 0.92 (SD 0.14). PPS+ at baseline was a significant predictor of QoL at 3 months after adjusting for socio-demographic and baseline clinical variables.CONCLUSIONS:
PPSs were associated with less improvement in QoL in patients receiving treatment for MDD, independent of severity of depression.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Dolor
/
Calidad de Vida
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Trastorno Depresivo Mayor
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
País/Región como asunto:
Asia
Idioma:
En
Año:
2015
Tipo del documento:
Article