[The French National Compound Library: advances and future prospects]. / Chimiothèque Nationale - Avancées et perspectives.
Med Sci (Paris)
; 31(4): 417-22, 2015 Apr.
Article
en Fr
| MEDLINE
| ID: mdl-25958760
ABSTRACT
The French National Compound Library (Chimiothèque Nationale) has been created in 2003 and is the federation of local collections. It contains more than 56 000 small molecules and natural compounds synthesised or isolated in different laboratories over the past years. This explains the diversity of the collection. The strength of this initiative is the ability to connect chemists and biologists for the development of hits. This development involves the synthesis of analogues or/and chemical tools to find new targets. These collaborations lead to the identification of new chemical probes. These probes able to modulate a biological function are essential to study biological pathways. They can also be useful for therapeutic applications. This article will describe the major achievements and perspectives of the French Chemical Library.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Bibliotecas de Moléculas Pequeñas
Tipo de estudio:
Prognostic_studies
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
Fr
Año:
2015
Tipo del documento:
Article