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Targeted gene correction of RUNX1 in induced pluripotent stem cells derived from familial platelet disorder with propensity to myeloid malignancy restores normal megakaryopoiesis.
Iizuka, Hiromitsu; Kagoya, Yuki; Kataoka, Keisuke; Yoshimi, Akihide; Miyauchi, Masashi; Taoka, Kazuki; Kumano, Keiki; Yamamoto, Takashi; Hotta, Akitsu; Arai, Shunya; Kurokawa, Mineo.
Afiliación
  • Iizuka H; Department of Hematology & Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan.
  • Kagoya Y; Department of Hematology & Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan.
  • Kataoka K; Department of Hematology & Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan.
  • Yoshimi A; Department of Hematology & Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan.
  • Miyauchi M; Department of Hematology & Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan.
  • Taoka K; Department of Hematology & Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan.
  • Kumano K; Department of Hematology & Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan.
  • Yamamoto T; Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, Higashi-Hiroshima, Japan.
  • Hotta A; Department of Reprogramming Science, Center for iPS cell Research and Applications (CiRA), and Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto, Japan; PRESTO, Japan Science and Technology Agency (JST), Tokyo, Japan.
  • Arai S; Department of Hematology & Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan.
  • Kurokawa M; Department of Hematology & Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan. Electronic address: kurokawa-tky@umin.ac.jp.
Exp Hematol ; 43(10): 849-57, 2015 Oct.
Article en En | MEDLINE | ID: mdl-26021490
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trastornos de las Plaquetas Sanguíneas / Terapia Genética / Leucemia Mieloide Aguda / Codón sin Sentido / Trastornos de la Coagulación Sanguínea Heredados / Trombopoyesis / Subunidad alfa 2 del Factor de Unión al Sitio Principal / Células Madre Pluripotentes Inducidas Límite: Adult / Female / Humans Idioma: En Año: 2015 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trastornos de las Plaquetas Sanguíneas / Terapia Genética / Leucemia Mieloide Aguda / Codón sin Sentido / Trastornos de la Coagulación Sanguínea Heredados / Trombopoyesis / Subunidad alfa 2 del Factor de Unión al Sitio Principal / Células Madre Pluripotentes Inducidas Límite: Adult / Female / Humans Idioma: En Año: 2015 Tipo del documento: Article