Role of Aspergillus fumigatus in Triggering Protease-Activated Receptor-2 in Airway Epithelial Cells and Skewing the Cells toward a T-helper 2 Bias.

Homma, Tetsuya; Kato, Atsushi; Bhushan, Bharat; Norton, James E; Suh, Lydia A; Carter, Roderick G; Gupta, Dave S; Schleimer, Robert P

Homma, Tetsuya; Kato, Atsushi; Bhushan, Bharat; Norton, James E; Suh, Lydia A; Carter, Roderick G; Gupta, Dave S; Schleimer, Robert P.

Afiliación

Homma T; 1 Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Kato A; 2 Division of Respiratory Medicine and Allergology, Department of Internal Medicine, Showa University School of Medicine, Tokyo, Japan.
Bhushan B; 1 Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Norton JE; 3 Division of Otolaryngology-Head and Neck Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago and the Northwestern University Feinberg School of Medicine, Chicago, Illinois; and.
Suh LA; 1 Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Carter RG; 1 Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Gupta DS; 1 Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Schleimer RP; 4 Department of Medicine, Michigan State University College of Human Medicine, East Lansing, Michigan.

Am J Respir Cell Mol Biol ; 54(1): 60-70, 2016 Jan.

Article en En | MEDLINE | ID: mdl-26072921

Asunto(s)

Aspergillus fumigatus/inmunología; Células Epiteliales/inmunología; Receptor PAR-2/inmunología; Mucosa Respiratoria/inmunología; Células Th2/inmunología; Aspergillus fumigatus/metabolismo; Aspergillus fumigatus/patogenicidad; Células Cultivadas; Quimiocina CXCL10/genética; Quimiocina CXCL10/inmunología; Quimiocina CXCL10/metabolismo; Células Epiteliales/efectos de los fármacos; Células Epiteliales/metabolismo; Células Epiteliales/microbiología; Células Epiteliales/virología; Regulación de la Expresión Génica; Interacciones Huésped-Patógeno; Humanos; Factor 3 Regulador del Interferón/inmunología; Factor 3 Regulador del Interferón/metabolismo; Poli I-C/farmacología; Proteína Tirosina Fosfatasa no Receptora Tipo 11/genética; Proteína Tirosina Fosfatasa no Receptora Tipo 11/inmunología; Proteína Tirosina Fosfatasa no Receptora Tipo 11/metabolismo; Receptor PAR-2/genética; Receptor PAR-2/metabolismo; Mucosa Respiratoria/efectos de los fármacos; Mucosa Respiratoria/metabolismo; Mucosa Respiratoria/microbiología; Mucosa Respiratoria/virología; Rhinovirus/inmunología; Rhinovirus/patogenicidad; Transducción de Señal; Células TH1/inmunología; Células TH1/metabolismo; Células Th2/efectos de los fármacos; Células Th2/metabolismo; Células Th2/microbiología; Células Th2/virología; Factores de Tiempo; Transfección

Palabras clave

Aspergillus fumigatus; CRS; asthma; bronchial epithelial cells; virus

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Aspergillus fumigatus / Células Th2 / Mucosa Respiratoria / Receptor PAR-2 / Células Epiteliales Idioma: En Año: 2016 Tipo del documento: Article

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