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Specific hepatic delivery of procollagen α1(I) small interfering RNA in lipid-like nanoparticles resolves liver fibrosis.
Jiménez Calvente, Carolina; Sehgal, Alfica; Popov, Yury; Kim, Yong Ook; Zevallos, Victor; Sahin, Ugur; Diken, Mustafa; Schuppan, Detlef.
Afiliación
  • Jiménez Calvente C; Institute of Translational Immunology, University of Mainz Medical Center, Mainz, Germany.
  • Sehgal A; Research Center for Immunotherapy, University of Mainz Medical Center, Mainz, Germany.
  • Popov Y; Alnylam Pharmaceuticals, Cambridge, MA.
  • Kim YO; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
  • Zevallos V; Institute of Translational Immunology, University of Mainz Medical Center, Mainz, Germany.
  • Sahin U; Research Center for Immunotherapy, University of Mainz Medical Center, Mainz, Germany.
  • Diken M; Institute of Translational Immunology, University of Mainz Medical Center, Mainz, Germany.
  • Schuppan D; Research Center for Immunotherapy, University of Mainz Medical Center, Mainz, Germany.
Hepatology ; 62(4): 1285-97, 2015 Oct.
Article en En | MEDLINE | ID: mdl-26096209
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sistemas de Liberación de Medicamentos / Colágeno Tipo I / ARN Interferente Pequeño / Nanopartículas / Tratamiento con ARN de Interferencia / Cirrosis Hepática Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sistemas de Liberación de Medicamentos / Colágeno Tipo I / ARN Interferente Pequeño / Nanopartículas / Tratamiento con ARN de Interferencia / Cirrosis Hepática Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article