Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate.

Trésaugues, Lionel; Lundbäck, Thomas; Welin, Martin; Flodin, Susanne; Nyman, Tomas; Silvander, Camilla; Gräslund, Susanne; Nordlund, Pär

Trésaugues, Lionel; Lundbäck, Thomas; Welin, Martin; Flodin, Susanne; Nyman, Tomas; Silvander, Camilla; Gräslund, Susanne; Nordlund, Pär.

Afiliación

Trésaugues L; Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden; Division of Biophysics, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Lundbäck T; Chemical Biology Consortium Sweden, Science for Life Laboratories, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden.
Welin M; Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Flodin S; Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Nyman T; Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Silvander C; Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Gräslund S; Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Nordlund P; Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden; Division of Biophysics, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden; Centre for Biomedical Structural Biology, School of Biolog

PLoS One ; 10(6): e0131507, 2015.

Article en En | MEDLINE | ID: mdl-26121039

Asunto(s)

Inosina Monofosfato/metabolismo; Pirofosfatasas/química; Pirofosfatasas/metabolismo; Adenosina Difosfato/metabolismo; Biocatálisis/efectos de los fármacos; Calorimetría; Secuencia Conservada; Cristalografía por Rayos X; Humanos; Inosina Monofosfato/farmacología; Cinética; Unión Proteica/efectos de los fármacos; Multimerización de Proteína/efectos de los fármacos; Relación Estructura-Actividad; Especificidad por Sustrato/efectos de los fármacos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirofosfatasas / Inosina Monofosfato Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirofosfatasas / Inosina Monofosfato Límite: Humans Idioma: En Año: 2015 Tipo del documento: Article