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The 2',4'-dihydroxychalcone could be explored to develop new inhibitors against the glycerol-3-phosphate dehydrogenase from Leishmania species.
Passalacqua, Thais G; Torres, Fábio A E; Nogueira, Camila T; de Almeida, Leticia; Del Cistia, Mayara L; dos Santos, Mariana B; Dutra, Luis A; Bolzani, Vanderlan da Silva; Regasini, Luis O; Graminha, Márcia A S; Marchetto, Reinaldo; Zottis, Aderson.
Afiliación
  • Passalacqua TG; UNESP-School of Pharmaceutical Sciences, Department of Clinical Analyses, Rodovia Araraquara-Jaú, Km 01, Araraquara, SP 14801-902, Brazil.
  • Torres FA; UNESP-School of Pharmaceutical Sciences, Department of Clinical Analyses, Rodovia Araraquara-Jaú, Km 01, Araraquara, SP 14801-902, Brazil.
  • Nogueira CT; UNESP-School of Pharmaceutical Sciences, Department of Clinical Analyses, Rodovia Araraquara-Jaú, Km 01, Araraquara, SP 14801-902, Brazil.
  • de Almeida L; UNESP-School of Pharmaceutical Sciences, Department of Clinical Analyses, Rodovia Araraquara-Jaú, Km 01, Araraquara, SP 14801-902, Brazil.
  • Del Cistia ML; UNESP-School of Pharmaceutical Sciences, Department of Clinical Analyses, Rodovia Araraquara-Jaú, Km 01, Araraquara, SP 14801-902, Brazil.
  • dos Santos MB; UNESP-Institute of Biosciences, Letters and Exact Sciences, Department of Chemistry and Environmental Sciences, Rua Cristóvão Colombo, 2265, Jardim Nazareth, São José do Rio Preto, SP 15054-000, Brazil.
  • Regasini LO; UNESP-Institute of Biosciences, Letters and Exact Sciences, Department of Chemistry and Environmental Sciences, Rua Cristóvão Colombo, 2265, Jardim Nazareth, São José do Rio Preto, SP 15054-000, Brazil.
  • Graminha MA; UNESP-School of Pharmaceutical Sciences, Department of Clinical Analyses, Rodovia Araraquara-Jaú, Km 01, Araraquara, SP 14801-902, Brazil.
  • Marchetto R; UNESP-Institute of Chemistry, Department of Biochemistry and Chemical Technology, Rua Professor Francisco Degni, 55, Caixa Postal 355, Araraquara, SP 14800-060, Brazil.
  • Zottis A; UNESP-Institute of Chemistry, Department of Biochemistry and Chemical Technology, Rua Professor Francisco Degni, 55, Caixa Postal 355, Araraquara, SP 14800-060, Brazil. Electronic address: zottisad@gmail.com.
Bioorg Med Chem Lett ; 25(17): 3564-8, 2015 09 01.
Article en En | MEDLINE | ID: mdl-26169126
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Chalconas / Glicerolfosfato Deshidrogenasa / Leishmania / Antiprotozoarios Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Chalconas / Glicerolfosfato Deshidrogenasa / Leishmania / Antiprotozoarios Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article