Platypnoea-orthodeoxia syndrome, an underdiagnosed cause of hypoxaemia: four cases and the possible underlying mechanisms.

Nassif, M; Lu, H; Konings, T C; Bouma, B J; Vonk Noordegraaf, A; Straver, B; Blom, N A; Clur, S A; Backx, A P C M; Groenink, M; Boekholdt, S M; Koolbergen, D R; Hazekamp, M G; Mulder, B J M; de Winter, R J

Nassif, M; Lu, H; Konings, T C; Bouma, B J; Vonk Noordegraaf, A; Straver, B; Blom, N A; Clur, S A; Backx, A P C M; Groenink, M; Boekholdt, S M; Koolbergen, D R; Hazekamp, M G; Mulder, B J M; de Winter, R J.

Afiliación

Nassif M; Department of Cardiology, Cardiac Catheterization Laboratory, Academic Medical Center-University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands. r.j.dewinter@amc.uva.nl.
Lu H; Department of Cardiology, Cardiac Catheterization Laboratory, Academic Medical Center-University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands.
Konings TC; Department of Cardiology, VU University Medical Center, Amsterdam, The Netherlands.
Bouma BJ; Department of Cardiology, Cardiac Catheterization Laboratory, Academic Medical Center-University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands.
Vonk Noordegraaf A; Department of Pulmonary Medicine, VU University Medical Center, Amsterdam, The Netherlands.
Straver B; Department of Cardiology, Cardiac Catheterization Laboratory, Academic Medical Center-University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands.
Blom NA; Department of Pediatric Cardiology, Academic Medical Center, Amsterdam, The Netherlands.
Clur SA; Department of Cardiology, Cardiac Catheterization Laboratory, Academic Medical Center-University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands.
Backx AP; Department of Pediatric Cardiology, Academic Medical Center, Amsterdam, The Netherlands.
Groenink M; Department of Pediatric Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Boekholdt SM; Department of Pediatric Cardiology, Academic Medical Center, Amsterdam, The Netherlands.
Koolbergen DR; Department of Cardiology, Cardiac Catheterization Laboratory, Academic Medical Center-University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands.
Hazekamp MG; Department of Cardiology, Cardiac Catheterization Laboratory, Academic Medical Center-University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands.
Mulder BJ; Department of Cardiology, Cardiac Catheterization Laboratory, Academic Medical Center-University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands.
de Winter RJ; Department of Cardiothoracic Surgery, Academic Medical Center, Amsterdam, The Netherlands.

Neth Heart J ; 23(11): 539-45, 2015 Nov.

Article en En | MEDLINE | ID: mdl-26170192

ABSTRACT

ABSTRACT

Cardiac platypnoea-orthodeoxia syndrome (POS) is a position-dependent condition of dyspnoea and hypoxaemia due to right-to-left shunting. It often remains unrecognised in clinical practice, possibly because of its complex underlying pathophysiology. We present four consecutive patients with POS and patent foramen ovale (PFO) who underwent a successful percutaneous PFO closure, describe the mechanism of their POS and provide a review of the literature.

Palabras clave

Atrial septum; Dyspnoea; Foramen ovale, patent; Mechanism; Platypnoea-orthodeoxia

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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2015 Tipo del documento: Article

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