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Palladium-Catalyzed Synthesis of Phenanthridine/Benzoxazine-Fused Quinazolinones by Intramolecular C-H Bond Activation.
Gupta, Puneet K; Yadav, Nisha; Jaiswal, Subodh; Asad, Mohd; Kant, Ruchir; Hajela, Kanchan.
Afiliación
  • Gupta PK; Division of Medicinal and Process Chemistry, CSIR-Central Drug, Research Institute, BS-10/1, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031 (India), Fax:(+91) 522-2623405, -2623938.
  • Yadav N; Division of Medicinal and Process Chemistry, CSIR-Central Drug, Research Institute, BS-10/1, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031 (India), Fax:(+91) 522-2623405, -2623938.
  • Jaiswal S; Division of Medicinal and Process Chemistry, CSIR-Central Drug, Research Institute, BS-10/1, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031 (India), Fax:(+91) 522-2623405, -2623938.
  • Asad M; Division of Medicinal and Process Chemistry, CSIR-Central Drug, Research Institute, BS-10/1, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031 (India), Fax:(+91) 522-2623405, -2623938.
  • Kant R; Molecular and Structural Biology Division, CSIR-Central Drug Research Institute, BS-10/1, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031 (India).
  • Hajela K; Division of Medicinal and Process Chemistry, CSIR-Central Drug, Research Institute, BS-10/1, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031 (India), Fax:(+91) 522-2623405, -2623938. kanchan_hajela@cdri.res.in.
Chemistry ; 21(38): 13210-5, 2015 Sep 14.
Article en En | MEDLINE | ID: mdl-26230355
ABSTRACT
A highly efficient synthesis of phenanthridine/benzoxazine-fused quinazolinones by ligand-free palladium-catalyzed intramolecular C-H bond activation under mild conditions has been developed. The C-C coupling provides the corresponding N-fused polycyclic heterocycles in good to excellent yields and with wide functional group tolerance.
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2015 Tipo del documento: Article
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2015 Tipo del documento: Article