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RAF inhibitors that evade paradoxical MAPK pathway activation.
Zhang, Chao; Spevak, Wayne; Zhang, Ying; Burton, Elizabeth A; Ma, Yan; Habets, Gaston; Zhang, Jiazhong; Lin, Jack; Ewing, Todd; Matusow, Bernice; Tsang, Garson; Marimuthu, Adhirai; Cho, Hanna; Wu, Guoxian; Wang, Weiru; Fong, Daniel; Nguyen, Hoa; Shi, Songyuan; Womack, Patrick; Nespi, Marika; Shellooe, Rafe; Carias, Heidi; Powell, Ben; Light, Emily; Sanftner, Laura; Walters, Jason; Tsai, James; West, Brian L; Visor, Gary; Rezaei, Hamid; Lin, Paul S; Nolop, Keith; Ibrahim, Prabha N; Hirth, Peter; Bollag, Gideon.
Afiliación
  • Zhang C; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Spevak W; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Zhang Y; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Burton EA; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Ma Y; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Habets G; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Zhang J; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Lin J; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Ewing T; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Matusow B; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Tsang G; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Marimuthu A; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Cho H; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Wu G; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Wang W; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Fong D; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Nguyen H; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Shi S; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Womack P; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Nespi M; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Shellooe R; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Carias H; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Powell B; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Light E; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Sanftner L; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Walters J; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Tsai J; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • West BL; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Visor G; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Rezaei H; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Lin PS; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Nolop K; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Ibrahim PN; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Hirth P; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
  • Bollag G; Plexxikon Inc., 91 Bolivar Drive, Berkeley, California 94710, USA.
Nature ; 526(7574): 583-6, 2015 Oct 22.
Article en En | MEDLINE | ID: mdl-26466569
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Quinasas Activadas por Mitógenos / Sistema de Señalización de MAP Quinasas / Proteínas Proto-Oncogénicas B-raf / Inhibidores de Proteínas Quinasas Límite: Animals / Female / Humans Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
XML
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Quinasas Activadas por Mitógenos / Sistema de Señalización de MAP Quinasas / Proteínas Proto-Oncogénicas B-raf / Inhibidores de Proteínas Quinasas Límite: Animals / Female / Humans Idioma: En Año: 2015 Tipo del documento: Article