Antitumor activity of amidino-substituted benzimidazole and benzimidazo[1,2-a]quinoline derivatives tested in 2D and 3D cell culture systems.

Brajsa, Karmen; Vujasinovic, Ines; Jelic, Dubravko; Trzun, Marija; Zlatar, Ivo; Karminski-Zamola, Grace; Hranjec, Marijana

Brajsa, Karmen; Vujasinovic, Ines; Jelic, Dubravko; Trzun, Marija; Zlatar, Ivo; Karminski-Zamola, Grace; Hranjec, Marijana.

Afiliación

Brajsa K; a Pharmacology in Vitro , Zagreb , Croatia .
Vujasinovic I; b Chemistry, Fidelta D.O.O. , Zagreb , Croatia , and.
Jelic D; a Pharmacology in Vitro , Zagreb , Croatia .
Trzun M; a Pharmacology in Vitro , Zagreb , Croatia .
Zlatar I; a Pharmacology in Vitro , Zagreb , Croatia .
Karminski-Zamola G; c Department of Organic Chemistry , Faculty of Chemical Engineering and Technology, University of Zagreb , Zagreb , Croatia.
Hranjec M; c Department of Organic Chemistry , Faculty of Chemical Engineering and Technology, University of Zagreb , Zagreb , Croatia.

J Enzyme Inhib Med Chem ; 31(6): 1139-45, 2016 Dec.

Article en En | MEDLINE | ID: mdl-26505692

Asunto(s)

Antineoplásicos/farmacología; Bencimidazoles/farmacología; Quinolonas/farmacología; Antineoplásicos/química; Línea Celular Tumoral; Humanos; Relación Estructura-Actividad

Palabras clave

2D and 3D in vitro cytotoxicity assay; amidines; antitumor activity; benzimidazo[1,2-a]quinolines; benzimidazoles

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Bencimidazoles / Quinolonas / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article

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