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Small Molecules Take A Big Step Against Clostridium difficile.
Beilhartz, Greg L; Tam, John; Melnyk, Roman A.
Afiliación
  • Beilhartz GL; Molecular Structure & Function, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada.
  • Tam J; Molecular Structure & Function, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada.
  • Melnyk RA; Molecular Structure & Function, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: roman.melnyk@sickkids.ca.
Trends Microbiol ; 23(12): 746-748, 2015 Dec.
Article en En | MEDLINE | ID: mdl-26547239
ABSTRACT
Effective treatment of Clostridium difficile infections demands a shift away from antibiotics towards toxin-neutralizing agents. Work by Bender et al., using a drug that attenuates toxin action in vivo without affecting bacterial survival, demonstrates the exciting potential of small molecules as a new modality in the fight against C. difficile.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Virulencia / Clostridioides difficile / Infecciones por Clostridium / Antibacterianos Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Virulencia / Clostridioides difficile / Infecciones por Clostridium / Antibacterianos Límite: Animals Idioma: En Año: 2015 Tipo del documento: Article