Long-awaited news for hepatic veno-occlusive disease.
Blood
; 127(13): 1630-1, 2016 Mar 31.
Article
en En
| MEDLINE
| ID: mdl-27034420
ABSTRACT
In this issue of Blood, Palomo et al provide new insight into the mechanism of action of defibrotide as an endothelial protective agent, while Richardson et al present the encouraging final results of the phase 3 clinical study of defibrotide for the treatment of severe hepatic veno-occlusive disease (VOD), showing a 23% improvement in day +100 survival after hematopoietic cell transplantation (HCT) compared with historical control.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Polidesoxirribonucleótidos
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Enfermedad Veno-Oclusiva Hepática
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Células Endoteliales de la Vena Umbilical Humana
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Fibrinolíticos
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Insuficiencia Multiorgánica
Límite:
Female
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Humans
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Male
Idioma:
En
Año:
2016
Tipo del documento:
Article