Ex vivo foam cell formation is enhanced in monocytes from older individuals by both extrinsic and intrinsic mechanisms.

Angelovich, Thomas A; Shi, Margaret D Y; Zhou, Jingling; Maisa, Anna; Hearps, Anna C; Jaworowski, Anthony

Angelovich, Thomas A; Shi, Margaret D Y; Zhou, Jingling; Maisa, Anna; Hearps, Anna C; Jaworowski, Anthony.

Afiliación

Angelovich TA; Centre for Biomedical Research, Burnet Institute, 85 Commercial Road, Melbourne, Victoria 3004, Australia; School of Applied Sciences, RMIT University, GPO Box 2476, Melbourne, Victoria 3001, Australia.
Shi MD; Centre for Biomedical Research, Burnet Institute, 85 Commercial Road, Melbourne, Victoria 3004, Australia.
Zhou J; Centre for Biomedical Research, Burnet Institute, 85 Commercial Road, Melbourne, Victoria 3004, Australia.
Maisa A; Centre for Biomedical Research, Burnet Institute, 85 Commercial Road, Melbourne, Victoria 3004, Australia.
Hearps AC; Centre for Biomedical Research, Burnet Institute, 85 Commercial Road, Melbourne, Victoria 3004, Australia; Department of Infectious Diseases, Monash University, Level 2 85 Commercial Road, Melbourne, Victoria 3004, Australia.
Jaworowski A; Centre for Biomedical Research, Burnet Institute, 85 Commercial Road, Melbourne, Victoria 3004, Australia; Department of Infectious Diseases, Monash University, Level 2 85 Commercial Road, Melbourne, Victoria 3004, Australia; Department of Immunology, Monash University, Level 6 89 Commercial Road, M

Exp Gerontol ; 80: 17-26, 2016 07.

Article en En | MEDLINE | ID: mdl-27073169

Asunto(s)

Envejecimiento/metabolismo; Aterosclerosis/fisiopatología; Colesterol/metabolismo; Células Espumosas/citología; Macrófagos/citología; Monocitos/citología; Transportador 1 de Casete de Unión a ATP/genética; Transportador 1 de Casete de Unión a ATP/metabolismo; Acilcoenzima A/genética; Acilcoenzima A/metabolismo; Adulto; Anciano; Anciano de 80 o más Años; Australia; Transporte Biológico; Estudios Transversales; Células Espumosas/patología; Regulación de la Expresión Génica; Humanos; Inflamación/metabolismo; Masculino; Persona de Mediana Edad; Migración Transendotelial y Transepitelial; Adulto Joven

Palabras clave

Age-related disease; Atherosclerosis; Foam cells; Inflammation; Monocytes

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Envejecimiento / Monocitos / Colesterol / Aterosclerosis / Células Espumosas / Macrófagos Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Humans / Male / Middle aged País/Región como asunto: Oceania Idioma: En Año: 2016 Tipo del documento: Article

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