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Landscape of somatic mutations in 560 breast cancer whole-genome sequences.
Nik-Zainal, Serena; Davies, Helen; Staaf, Johan; Ramakrishna, Manasa; Glodzik, Dominik; Zou, Xueqing; Martincorena, Inigo; Alexandrov, Ludmil B; Martin, Sancha; Wedge, David C; Van Loo, Peter; Ju, Young Seok; Smid, Marcel; Brinkman, Arie B; Morganella, Sandro; Aure, Miriam R; Lingjærde, Ole Christian; Langerød, Anita; Ringnér, Markus; Ahn, Sung-Min; Boyault, Sandrine; Brock, Jane E; Broeks, Annegien; Butler, Adam; Desmedt, Christine; Dirix, Luc; Dronov, Serge; Fatima, Aquila; Foekens, John A; Gerstung, Moritz; Hooijer, Gerrit K J; Jang, Se Jin; Jones, David R; Kim, Hyung-Yong; King, Tari A; Krishnamurthy, Savitri; Lee, Hee Jin; Lee, Jeong-Yeon; Li, Yilong; McLaren, Stuart; Menzies, Andrew; Mustonen, Ville; O'Meara, Sarah; Pauporté, Iris; Pivot, Xavier; Purdie, Colin A; Raine, Keiran; Ramakrishnan, Kamna; Rodríguez-González, F Germán; Romieu, Gilles.
Afiliación
  • Nik-Zainal S; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Davies H; East Anglian Medical Genetics Service, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 9NB, UK.
  • Staaf J; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Ramakrishna M; Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund SE-223 81, Sweden.
  • Glodzik D; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Zou X; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Martincorena I; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Alexandrov LB; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Martin S; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Wedge DC; Theoretical Biology and Biophysics (T-6), Los Alamos National Laboratory, Los Alamos, NM 87545, New Mexico, USA.
  • Van Loo P; Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA.
  • Ju YS; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Smid M; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Brinkman AB; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Morganella S; Department of Human Genetics, University of Leuven, B-3000 Leuven, Belgium.
  • Aure MR; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Lingjærde OC; Department of Medical Oncology, Erasmus MC Cancer Institute and Cancer Genomics Netherlands, Erasmus University Medical Center, Rotterdam 3015CN, The Netherlands.
  • Langerød A; Radboud University, Department of Molecular Biology, Faculty of Science, 6525GA Nijmegen, The Netherlands.
  • Ringnér M; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
  • Ahn SM; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, Oslo 0310, Norway.
  • Boyault S; K. G. Jebsen Centre for Breast Cancer Research, Institute for Clinical Medicine, University of Oslo, Oslo 0310, Norway.
  • Brock JE; K. G. Jebsen Centre for Breast Cancer Research, Institute for Clinical Medicine, University of Oslo, Oslo 0310, Norway.
  • Broeks A; Department of Computer Science, University of Oslo, Oslo, Norway.
  • Butler A; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, Oslo 0310, Norway.
  • Desmedt C; K. G. Jebsen Centre for Breast Cancer Research, Institute for Clinical Medicine, University of Oslo, Oslo 0310, Norway.
  • Dirix L; Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund SE-223 81, Sweden.
  • Dronov S; Gachon Institute of Genome Medicine and Science, Gachon University Gil Medical Center, Incheon, South Korea.
  • Fatima A; Translational Research Lab, Centre Léon Bérard, 28, rue Laënnec, 69373 Lyon Cedex 08, France.
  • Foekens JA; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
  • Gerstung M; The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • Hooijer GK; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Jang SJ; Breast Cancer Translational Research Laboratory, Université Libre de Bruxelles, Institut Jules Bordet, Bd de Waterloo 121, B-1000 Brussels, Belgium.
  • Jones DR; Translational Cancer Research Unit, Center for Oncological Research, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
  • Kim HY; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • King TA; Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Krishnamurthy S; Department of Medical Oncology, Erasmus MC Cancer Institute and Cancer Genomics Netherlands, Erasmus University Medical Center, Rotterdam 3015CN, The Netherlands.
  • Lee HJ; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Lee JY; Department of Pathology, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
  • Li Y; Department of Pathology, Asan Medical Center, College of Medicine, Ulsan University, Ulsan, South Korea.
  • McLaren S; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Menzies A; Department of Pathology, College of Medicine, Hanyang University, Seoul 133-791, South Korea.
  • Mustonen V; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA.
  • O'Meara S; Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard., Houston, Texas 77030, USA.
  • Pauporté I; Department of Pathology, Asan Medical Center, College of Medicine, Ulsan University, Ulsan, South Korea.
  • Pivot X; Institute for Bioengineering and Biopharmaceutical Research (IBBR), Hanyang University, Seoul, South Korea.
  • Purdie CA; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Raine K; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Ramakrishnan K; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Rodríguez-González FG; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Romieu G; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
Nature ; 534(7605): 47-54, 2016 06 02.
Article en En | MEDLINE | ID: mdl-27135926
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Genoma Humano / Mutación Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans / Male Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Genoma Humano / Mutación Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans / Male Idioma: En Año: 2016 Tipo del documento: Article