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Could drugs inhibiting the mevalonate pathway also target cancer stem cells?
Likus, Wirginia; Siemianowicz, Krzysztof; Bienk, Konrad; Pakula, Malgorzata; Pathak, Himani; Dutta, Chhanda; Wang, Qiong; Shojaei, Shahla; Assaraf, Yehuda G; Ghavami, Saeid; Cieslar-Pobuda, Artur; Los, Marek J.
Afiliación
  • Likus W; Department of Human Anatomy, School of Medicine in Katowice, Medical University of Silesia, 18 Medyków Street, 40-752 Katowice, Poland.
  • Siemianowicz K; Department of Biochemistry, School of Medicine in Katowice, Medical University of Silesia, 18 Medyków Street, 40-752 Katowice, Poland.
  • Bienk K; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, DK-8000 Aarhus C, Denmark.
  • Pakula M; Department of Biomedicine, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Pathak H; Indian Institute of Science Education and Research (IISER TVM), Thiruvananthapuram, Kerala, India.
  • Dutta C; Department of Clinical & Experimental Medicine (IKE), Linköping University, Linköping, Sweden.
  • Wang Q; Department of Physics, Chemistry and Biology (IFM), Division of Biotechnology, Linköping University, Linköping, Sweden.
  • Shojaei S; Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Assaraf YG; The Fred Wyszkowski Cancer Research Laboratory, Department of Biology, Technion-Israel Institute of Technology, Haifa 32000, Israel.
  • Ghavami S; Department of Human Anatomy and Cell Science, College of Medicine, Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada; Health Research Policy Center, Shiraz University of Medical Science, Shiraz, Iran.
  • Cieslar-Pobuda A; Institute of Automatic Control, Silesian University of Technology, Gliwice, Poland.
  • Los MJ; LinkoCare Life Sciences AB, 583 30 Linköping, Sweden; ENT Department, School of Medicine in Katowice, Medical University of Silesia, 20-24 Francuska Street, 40-027 Katowice, Poland. Electronic address: mjelos@gmail.com.
Drug Resist Updat ; 25: 13-25, 2016 03.
Article en En | MEDLINE | ID: mdl-27155373

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Inhibidores de Hidroximetilglutaril-CoA Reductasas / Ácido Mevalónico / Neoplasias Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Inhibidores de Hidroximetilglutaril-CoA Reductasas / Ácido Mevalónico / Neoplasias Límite: Animals / Humans Idioma: En Año: 2016 Tipo del documento: Article