Your browser doesn't support javascript.
loading
Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein.
Wang, Yu; Ding, Xiwei; Wang, Shaoqing; Moser, Catherine D; Shaleh, Hassan M; Mohamed, Essa A; Chaiteerakij, Roongruedee; Allotey, Loretta K; Chen, Gang; Miyabe, Katsuyuki; McNulty, Melissa S; Ndzengue, Albert; Barr Fritcher, Emily G; Knudson, Ryan A; Greipp, Patricia T; Clark, Karl J; Torbenson, Michael S; Kipp, Benjamin R; Zhou, Jie; Barrett, Michael T; Gustafson, Michael P; Alberts, Steven R; Borad, Mitesh J; Roberts, Lewis R.
Afiliación
  • Wang Y; Department of Hepatobiliary Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA.
  • Ding X; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA; Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
  • Wang S; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA; Department of Pathology, Qiqihar Medical University, Qiqihar, China.
  • Moser CD; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA.
  • Shaleh HM; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA.
  • Mohamed EA; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA.
  • Chaiteerakij R; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA.
  • Allotey LK; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA.
  • Chen G; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA.
  • Miyabe K; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA.
  • McNulty MS; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN, USA.
  • Ndzengue A; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA.
  • Barr Fritcher EG; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.
  • Knudson RA; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.
  • Greipp PT; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.
  • Clark KJ; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN, USA.
  • Torbenson MS; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.
  • Kipp BR; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.
  • Zhou J; Department of Hepatobiliary Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Barrett MT; Division of Hematology and Medical Oncology, Mayo Clinic College of Medicine, Phoenix, AZ, USA.
  • Gustafson MP; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.
  • Alberts SR; Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN, USA.
  • Borad MJ; Division of Hematology and Medical Oncology, Mayo Clinic College of Medicine, Phoenix, AZ, USA.
  • Roberts LR; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center, Rochester, MN, USA. Electronic address: roberts.lewis@mayo.edu.
Cancer Lett ; 380(1): 163-73, 2016 09 28.
Article en En | MEDLINE | ID: mdl-27216979
Asunto(s)
Antineoplásicos/farmacología; Neoplasias de los Conductos Biliares/tratamiento farmacológico; Colangiocarcinoma/tratamiento farmacológico; Proteínas del Citoesqueleto/metabolismo; Fusión Génica; Neoplasias Pulmonares/tratamiento farmacológico; Compuestos de Fenilurea/farmacología; Pirimidinas/farmacología; Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos/antagonistas & inhibidores; Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos/metabolismo; Animales; Apoptosis/efectos de los fármacos; Bencimidazoles/farmacología; Neoplasias de los Conductos Biliares/genética; Neoplasias de los Conductos Biliares/metabolismo; Neoplasias de los Conductos Biliares/patología; Proliferación Celular/efectos de los fármacos; Colangiocarcinoma/genética; Colangiocarcinoma/metabolismo; Colangiocarcinoma/secundario; Proteínas del Citoesqueleto/genética; Humanos; Imidazoles/farmacología; Subunidad gamma Común de Receptores de Interleucina/deficiencia; Subunidad gamma Común de Receptores de Interleucina/genética; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/secundario; Metaloproteinasa 2 de la Matriz/metabolismo; Metaloproteinasa 3 de la Matriz/metabolismo; Metaloproteinasa 9 de la Matriz/metabolismo; Ratones Endogámicos NOD; Ratones Noqueados; Ratones SCID; Piridazinas/farmacología; Quinolonas/farmacología; Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos/genética; Transducción de Señal/efectos de los fármacos; Factores de Tiempo; Carga Tumoral/efectos de los fármacos; Ensayos Antitumor por Modelo de Xenoinjerto
Palabras clave
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Compuestos de Fenilurea / Pirimidinas / Neoplasias de los Conductos Biliares / Colangiocarcinoma / Proteínas del Citoesqueleto / Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos / Fusión Génica / Neoplasias Pulmonares / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Compuestos de Fenilurea / Pirimidinas / Neoplasias de los Conductos Biliares / Colangiocarcinoma / Proteínas del Citoesqueleto / Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos / Fusión Génica / Neoplasias Pulmonares / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Año: 2016 Tipo del documento: Article