High oxidative stress adversely affects NF&#954;B mediated induction of inducible nitric oxide synthase in human neutrophils: Implications in chronic myeloid leukemia.

Singh, Abhishek Kumar; Awasthi, Deepika; Dubey, Megha; Nagarkoti, Sheela; Kumar, Ashutosh; Chandra, Tulika; Barthwal, Manoj Kumar; Tripathi, Anil Kumar; Dikshit, Madhu

High oxidative stress adversely affects NFκB mediated induction of inducible nitric oxide synthase in human neutrophils: Implications in chronic myeloid leukemia.

Singh, Abhishek Kumar; Awasthi, Deepika; Dubey, Megha; Nagarkoti, Sheela; Kumar, Ashutosh; Chandra, Tulika; Barthwal, Manoj Kumar; Tripathi, Anil Kumar; Dikshit, Madhu.

Afiliación

Singh AK; Pharmacology Division, CSIR-Central Drug Research Institute, Lucknow, India.
Awasthi D; Pharmacology Division, CSIR-Central Drug Research Institute, Lucknow, India.
Dubey M; Pharmacology Division, CSIR-Central Drug Research Institute, Lucknow, India.
Nagarkoti S; Pharmacology Division, CSIR-Central Drug Research Institute, Lucknow, India.
Kumar A; Department of Pathology, King George's Medical University, Lucknow, India.
Chandra T; Department of Transfusion Medicine, King George's Medical University, Lucknow, India.
Barthwal MK; Pharmacology Division, CSIR-Central Drug Research Institute, Lucknow, India.
Tripathi AK; Department of Clinical Haematology & Medical Oncology, King George's Medical University, Lucknow, India.
Dikshit M; Pharmacology Division, CSIR-Central Drug Research Institute, Lucknow, India. Electronic address: madhu_dikshit@cdri.res.in.

Nitric Oxide ; 58: 28-41, 2016 08 31.

Article en En | MEDLINE | ID: mdl-27264783

Asunto(s)

Leucemia Mielógena Crónica BCR-ABL Positiva/fisiopatología; FN-kappa B/metabolismo; Neutrófilos/enzimología; Óxido Nítrico Sintasa de Tipo II/antagonistas & inhibidores; Estrés Oxidativo/fisiología; Ditiotreitol/farmacología; Etilmaleimida/farmacología; Glutatión/metabolismo; Humanos; Células K562; NADPH Oxidasa 2/metabolismo; FN-kappa B/genética; Óxido Nítrico/metabolismo; Óxido Nítrico Sintasa de Tipo II/biosíntesis; Óxido Nítrico Sintasa de Tipo II/genética; Regiones Promotoras Genéticas; Especies Reactivas de Oxígeno/metabolismo

Palabras clave

Inducible nitric oxide synthase; NFκB; Nitric oxide; Reactive oxygen species; S-glutathionylation

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Leucemia Mielógena Crónica BCR-ABL Positiva / FN-kappa B / Estrés Oxidativo / Óxido Nítrico Sintasa de Tipo II / Neutrófilos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article

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