Rhegmatogenous retinal detachment following intravitreal ocriplasmin.
Graefes Arch Clin Exp Ophthalmol
; 254(12): 2333-2338, 2016 Dec.
Article
en En
| MEDLINE
| ID: mdl-27278373
ABSTRACT
PURPOSE:
To describe the characteristics and outcomes of patients presenting with rhegmatogenous retinal detachment (RRD) after ocriplasmin (OCP) injection.METHODS:
Retrospective, multi-centre, observational case series with case note review.RESULTS:
Eight patients with symptomatic vitreomacular traction (six with concomitant macular hole) were diagnosed with RRD after a median of 16 days (range 3-131 days) post-OCP injection. Presentation was within 3 weeks of the OCP injection in six of the cases. Five patients presented with symptoms post-OCP, and three were diagnosed asymptomatically on planned visits. Seven cases were phakic, one had high myopia (>8 dioptres), and two cases had lattice degeneration. Following RRD surgery, hole closure was achieved in 5/6 MH cases. The final median BCVA at 7 months was 20/80 (range 20/40-20/1200) similar to the baseline BCVA 20/80, with four patients gaining ≥1 line of vision compared to baseline but three losing ≥3 lines.CONCLUSIONS:
RRD is a non-negligible risk associated with intravitreal OCP, and it should be used with caution in eyes with high myopia and peripheral retinal pathology predisposing to RRD. Detailed peripheral retinal examination is recommended pre- and postoperatively at all visits. Patients should be advised to seek attention if symptoms recur after initial presentation.Palabras clave
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1
Banco de datos:
MEDLINE
Asunto principal:
Fragmentos de Péptidos
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Retina
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Desprendimiento de Retina
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Agudeza Visual
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Fibrinolisina
Tipo de estudio:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2016
Tipo del documento:
Article